Preferred Label : Topical Celecoxib;
NCIt synonyms : Celecoxib Cream; Celecoxib Topical;
NCIt definition : A topical cream formulation containing celecoxib, a nonsteroidal anti-inflammatory
drug (NSAID), with anti-inflammatory and potential keratolytic, chemopreventive and
antineoplastic activities. Upon topical application to the affected area, celecoxib
selectively binds to and inhibits cyclooxygenase-2 activity (COX-2), which may result
in localized keratinocyte apoptosis. The breakdown of keratinocytes prevents their
proliferation locally and may reduce tumor cell proliferation.;
Molecule name : DFD-07;
NCI Metathesaurus CUI : CL551149;
Origin ID : C148519;
UMLS CUI : C4725095;
Semantic type(s)
- concept_is_in_subset
