" /> Rubitecan - CISMeF





Preferred Label : Rubitecan;

NCIt synonyms : Nitrocamptothecin; 9-Nitro-20(S)-camptothecin; 9-nitrocamptothecin; 9-NC;

NCIt definition : A semisynthetic agent related to camptothecin with potent antitumor and antiviral properties. Rubitecan binds to and inhibits the enzyme topoisomerase I and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells; this agent also prevents repair of reversible single-strand DNA breaks. (NCI04);

Alternative definition : NCI-GLOSS: An alkaloid drug belonging to a class of anticancer agents called topoisomerase inhibitors.;

UNII : H19C446XXB;

InChIKey : VHXNKPBCCMUMSW-FQEVSTJZSA-N;

CAS number : 91421-42-0;

Drug name : Orathecin; Camptogen;

Molecule name : RFS 2000;

Chemical formula : C20H15N3O6;

NSC code : 603070;

Codes from synonyms : CDR0000045502;

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10/05/2025


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