Preferred Label : Allogeneic interleukin-17-producing CD8-positive T-cells;
NCIt definition : A preparation of allogeneic human cytotoxic T-lymphocytes that express the pro-inflammatory
cytokine interleukin-17 (IL-17; IL17), with potential immunomodulating and anti-tumor
activities. Upon ex vivo stimulation, the IL-17-producing CD8-positive T-cells (Tc17)
convert to interferon-gamma (IFNg; IFN-g)-producing CD8-positive T-cells (Tc1). Tc1
cells exert enhanced anti-tumor cytotoxicity. Human Tc17 cells may contribute to a
number of human inflammatory and malignant diseases.;
NCI Metathesaurus CUI : CL551046;
Origin ID : C148499;
UMLS CUI : C4725081;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
