Preferred Label : Bifidobacterium lactis/Lactobacillus acidophilus/Inulin Probiotic Supplement;
NCIt synonyms : B. lactis/L. acidophilus/Inulin Probiotic Supplement;
NCIt definition : A tablet probiotic supplement containing the polysaccharide inulin and the non-pathogenic
microorganisms Bifidobacterium lactis and Lactobacillus acidophilus, with potential
anti-inflammatory, immunomodulating and protective activities. Upon oral administration
of B. lactis/L. acidophilus/inulin probiotic supplement, the bacterial components
in this dietary supplement may improve digestion and promote adequate colonization
of the gastrointestinal (GI) tract by modulating the composition of the normal microflora.
During colonization in the GI tract, the bacteria may form a protective intestinal
barrier that may prevent both damage to the mucosal epithelia caused by toxins and
attachment of potential pathogens, which protects against bacterial translocation
and infection. In addition, this agent may both reduce the secretion of pro-inflammatory
cytokines, including interleukin-10, and potentiate natural and acquired immunity.
In colon cancer patients, these probiotic bacteria may favorably modulate the composition
of the colon cancer-associated microbiota and may increase expression of tumor-suppressing
genes. Inulin promotes growth and activity of beneficial GI bacteria, thereby altering
the endogenous flora further.;
Drug name : ProBion Clinica;
NCI Metathesaurus CUI : CL551062;
Origin ID : C148481;
UMLS CUI : C4725066;
Semantic type(s)
- concept_is_in_subset
