PFKFB4 wt Allele

Preferred Label : PFKFB4 wt Allele;

NCIt synonyms : 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 4 wt Allele;

NCIt definition : Human PFKFB4 wild-type allele is located in the vicinity of 3p21.31 and is approximately 45 kb in length. This allele, which encodes 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 protein, is involved in the regulation of glycolysis. Expression of the gene by hypoxic cancer cells is essential to their survival.;

NCI Metathesaurus CUI : CL550946;

GenBank Accession Number : BC010269;

Details

Origin ID

C148360;

UMLS CUI

C4723648;

OMIM relation
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3p21.31 [NCIt concept]
gene_is_element_in_pathway
- Fructose and Mannose Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- Carbohydrate Metabolic Process [NCIt concept]
- Dephosphorylation [NCIt concept]
- Glycolysis [NCIt concept]
- Hydrolysis [NCIt concept]
- Phosphorylation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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