Preferred Label : Donor-derived Cytokine-induced Memory-like Natural Killer Cells;
NCIt synonyms : Allogeneic CIML NKs; Allogeneic Cytokine-induced Memory-like NK Cell; Allogeneic CIML NK Cells;
NCIt definition : A population of donor-derived cytokine-induced, memory-like, cytotoxic natural killer
(NK) cells (CIML NKs), with potential antitumor activity. Allogeneic NK cells are
pre-activated ex vivo with various cytokines, which induces the differentiation of
the NK cells into CIML NK cells. The pretreated NK cells exhibit enhanced activation
and interferon-gamma (IFN-g) responses, and may exert enhanced cytotoxicity against
tumor cells. Upon administration, the CIML NKs may induce an anti-tumor immune response
and kill tumor cells.;
NCI Metathesaurus CUI : CL550859;
Origin ID : C148213;
UMLS CUI : C4724902;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
