NCIt definition : The lactate salt form of squalamine, an aminosterol isolated from tissues of the dogfish
shark Squalus acanthias. Possessing anti-angiogenic properties, squalamine inhibits
the sodium-hydrogen exchanger NHE3, resulting in suppression of endothelial cell proliferation
and migration. This agent also has broad-spectrum antimicrobial properties. (NCI04);
Alternative definition : NCI-GLOSS: A drug that belongs to the family of drugs called angiogenesis inhibitors.
It prevents the growth of new blood vessels into a solid tumor.;
UNII : 4WE915J1KX;
InChIKey : ZPYIELFRIYUVQP-BHBJEIPNSA-N;
CAS number : 320725-47-1;
Molecule name : MSI-1256F;
Chemical formula : C34H65N3O5S.C3H6O3.H2O;
NSC code : 715056;
Codes from synonyms : NSC0715056; 31697; CDR0000045995;