Preferred Label : Lactobacillus reuteri Probiotic Tablet;
NCIt synonyms : L. reuteri Probiotic; Lactobacillus reuteri Probiotic;
NCIt definition : A tablet containing a strain of the probiotic Gram-positive, naturally-occurring bacterium
Lactobacillus reuteri (L. reuteri), with potential antimicrobial, immunomodulatory
and protective activities. Upon oral administration of the L. reuteri probiotic tablet,
the Lactobacillus strain may improve digestion and help maintain adequate colonization
of the gastrointestinal (GI) tract by modulating the composition of the normal microflora.
During colonization of the GI tract, this bacterium adheres to human intestinal epithelial
cells, and activates intestinal epithelial proliferation; both of these processes
promote the formation and maintenance of a protective barrier, thereby preventing
the attachment of harmful pathogens. L. reuteri produces lactic acid and other substances
during fermentation, and creates an acidic environment that is unfavorable for pathogens,
thereby further protecting the intestinal mucosa against pathogen-induced damage and
loss of integrity of the intestinal mucosal barrier. Dietary supplementation with
this bacterium has been shown to decrease intestinal inflammation and enhance innate
and acquired immunity. Lactobacillus reuteri is naturally found in the GI tract.;
NCI Metathesaurus CUI : CL550800;
Origin ID : C148148;
UMLS CUI : C4724850;
Semantic type(s)
- concept_is_in_subset
