Adenoviral PSA Vaccine ETBX-071

Preferred Label : Adenoviral PSA Vaccine ETBX-071;

NCIt synonyms : Adenoviral PSA Prostate Cancer Vaccine ETBX-071;

NCIt related terms : ETBX-071;

NCIt definition : A cancer vaccine composed of a genetically engineered, replication-deficient adenovirus carrying the gene encoding human prostate-specific antigen (PSA), with potential immunostimulating and antineoplastic activities. Upon vaccination with the adenoviral-PSA vaccine ETBX-071, the adenovirus infects cells and expresses PSA. In turn, PSA activates the immune system and induces a cytotoxic T-lymphocyte (CTL) response against PSA-expressing tumor cells. PSA, a tumor associated antigen (TAA), is expressed by prostate epithelial cells and is overexpressed in prostate cancer.;

UNII : 68TF9SDE9N;

Molecule name : ETBX-071;

NCI Metathesaurus CUI : CL550802;

Details

Origin ID

C148142;

UMLS CUI

C4724845;

Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

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