PTPRO wt Allele

Preferred Label : PTPRO wt Allele;

NCIt synonyms : Protein Tyrosine Phosphatase, Receptor Type, O Gene; GLEPP1; R-PTP-O; PTP-OC; PTP Phi; PTP-U2; Protein Tyrosine Phosphatase, Receptor Type O wt Allele; NPHS6; PTPU2; PTPROT;

NCIt definition : Human PTPRO wild-type allele is located in the vicinity of 12p12.3 and is approximately 276 kb in length. This allele, which encodes receptor-type tyrosine-protein phosphatase O protein, plays a role in both glomerulus development and protein tyrosine phosphatase activity. Mutation of the gene may be associated with nephrotic syndrome.;

NCI Metathesaurus CUI : CL545746;

GenBank Accession Number : U20489;

Details

Origin ID

C147976;

UMLS CUI

C4553406;

Automatic exact mappings (from CISMeF team)
- Nephrotic syndrome, type 6 [OMIM Phenotype]
- Protein-tyrosine phosphatase, receptor-type, o [OMIM gene]
- protein tyrosine phosphatase receptor type O [ORDO Gene]
OMIM relation
- Protein-tyrosine phosphatase, receptor-type, o [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 12p12.3 [NCIt concept]
gene_plays_role_in_process
- Dephosphorylation [NCIt concept]
- Histogenic Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Organogenesis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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