Preferred Label : Milodistim;
NCIt synonyms : GM-CSF/IL3 Fusion Protein; GM-CSF/IL-3 Fusion Protein; Pixykine; Granulocyte-Macrophage Colony Stimulating Factor/Interleukin-3 Fusion Protein; 23-L-Leucine-27-L-aspartic acid-39-L-glutamic acid-colony-stimulating factor 2 (Human
Clone pHG25 Protein Moiety Reduced), (127-9')-protein with 9-Glycine-10-glycine-11-glycine-12-glycine-13-L-serine-14-glycine-15-glycine-16-glycine-18-glycine-19-L-serine-34-L-aspartic
acid-89-L-aspartic acid-9-152-interleukin 3 (human clone D11 Precursor Protein Moiety
Reduced);
NCIt definition : A recombinant fusion protein derived from the coding sequences of two growth factors,
interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF).
Milodistim exhibits greater receptor binding affinity and colony stimulating activity
than its parent cytokines. This agent stimulates proliferation of immature hematopoietic
cells and allows the stimulation and expansion of multi-lineage hematopoiesis from
immature bone marrow progenitor cells. (NCI04);
UNII : 1FEP5O76SH;
CAS number : 137463-76-4;
Molecule name : PIXY321;
NSC code : 645014;
Origin ID : C1477;
UMLS CUI : C4281727;
Semantic type(s)
- concept_is_in_subset
- is_component_of_chemotherapy_regimen
