NCIt definition : A synthetic, nonopiod, twenty-five amino acid polybasic peptide analogue of an omega-conotoxin
derived from the marine snail Conus magus with analgesic activity. Ziconotide appears
to block neuronal N-type voltage-sensitive calcium channels (NCCB), inhibiting transmission
from pain-sensing primary nociceptors. This agent may exhibit significant analgesic
activity in refractory pain.;
Alternative definition : NCI-GLOSS: A drug used in the treatment of chronic pain.;
UNII : 7I64C51O16;
CAS number : 107452-89-1;
Drug name : Prialt;
Molecule name : SNX-111;
Chemical formula : C102H172N36O32S7;
Codes from synonyms : CDR0000045568; CDR0000589104; CDR0000044477;