EGFR NP_005219.2:p.L792Y

Preferred Label : EGFR NP_005219.2:p.L792Y;

NCIt synonyms : Receptor Tyrosine-Protein Kinase erbB-1 L792Y; Proto-Oncogene c-ErbB-1 Leu792Tyr; Receptor Tyrosine-Protein Kinase erbB-1 Leu792Tyr; EGFR NP_005219.2:p.Leu792Tyr; EGFR L792Y; NP_005219.2:p.L792Y; Epidermal Growth Factor Receptor L792Y; EGFR p.L792Y; NP_005219.2:p.Leu792Tyr; EGFR Leu792Tyr; Epidermal Growth Factor Receptor Leu792Tyr; EGFR p.Leu792Tyr; Proto-Oncogene c-ErbB-1 L792Y;

NCIt definition : A change in the amino acid residue at position 792 in the epidermal growth factor receptor protein where leucine has been replaced by tyrosine.;

NCIt note : This variation may be associated with development of osimertinib resistance.;

NCI Metathesaurus CUI : CL545049;

Details

Origin ID

C147017;

UMLS CUI

C4687651;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
gene_product_sequence_variation_encoded_by_gene_mutant
- EGFR Exon 20 Mutation [NCIt concept]
- EGFR Gene Mutation [NCIt concept]
gene_product_variant_of_gene_product
- Epidermal Growth Factor Receptor [NCIt concept]
molecular_abnormality_involves_gene
- EGFR Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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