EGFR NP_005219.2:p.L792F

Preferred Label : EGFR NP_005219.2:p.L792F;

NCIt synonyms : Proto-Oncogene c-ErbB-1 Leu792Phe; EGFR L792F; Receptor Tyrosine-Protein Kinase erbB-1 Leu792Phe; NP_005219.2:p.L792F; Epidermal Growth Factor Receptor L792F; EGFR p.L792F; EGFR NP_005219.2:p.Leu792Phe; Proto-Oncogene c-ErbB-1 L792F; Receptor Tyrosine-Protein Kinase erbB-1 L792F; EGFR Leu792Phe; NP_005219.2:p.Leu792Phe; Epidermal Growth Factor Receptor Leu792Phe; EGFR p.Leu792Phe;

NCIt definition : A change in the amino acid residue at position 792 in the epidermal growth factor receptor protein where leucine has been replaced by phenylalanine.;

NCIt note : This variation may be associated with development of osimertinib resistance.;

NCI Metathesaurus CUI : CL545046;

Details

Origin ID

C147014;

UMLS CUI

C4687648;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
gene_product_sequence_variation_encoded_by_gene_mutant
- EGFR Exon 20 Mutation [NCIt concept]
- EGFR Gene Mutation [NCIt concept]
- EGFR NM_005228.3:c.2374C>T [NCIt concept]
gene_product_variant_of_gene_product
- Epidermal Growth Factor Receptor [NCIt concept]
molecular_abnormality_involves_gene
- EGFR Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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