EGFR NP_005219.2:p.C797A

Preferred Label : EGFR NP_005219.2:p.C797A;

NCIt synonyms : NP_005219.2:p.Cys797Ala; EGFR Cys797Ala; Epidermal Growth Factor Receptor Cys797Ala; EGFR p.Cys797Ala; Proto-Oncogene c-ErbB-1 Cys797Ala; Receptor Tyrosine-Protein Kinase erbB-1 Cys797Ala; EGFR NP_005219.2:p.Cys797Ala; NP_005219.2:p.C797A; EGFR C797A; Epidermal Growth Factor Receptor C797A; EGFR p.C797A; Proto-Oncogene c-ErbB-1 C797A; Receptor Tyrosine-Protein Kinase erbB-1 C797A;

NCIt definition : A change in the amino acid residue at position 797 in the epidermal growth factor receptor protein where cysteine has been replaced by alanine.;

NCIt note : This variation may be associated with development of osimertinib resistance.;

NCI Metathesaurus CUI : CL545044;

Details

Origin ID

C147012;

UMLS CUI

C4687646;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
gene_product_sequence_variation_encoded_by_gene_mutant
- EGFR Exon 20 Mutation [NCIt concept]
- EGFR Gene Mutation [NCIt concept]
gene_product_variant_of_gene_product
- Epidermal Growth Factor Receptor [NCIt concept]
molecular_abnormality_involves_gene
- EGFR Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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