Preferred Label : SMRT Sequencing;
NCIt synonyms : Single Molecule, Real-Time Sequencing; SMRT Sequencing Technology;
NCIt related terms : PacBio; PacBio SMRT;
NCIt definition : A proprietary third-generation DNA sequencing system from Pacific Biosciences that
uses zero-mode waveguides (ZMWs) and phospholinked nucleotides. A single DNA polymerase
enzyme is affixed at the bottom of a ZMW structure with a single molecule of DNA as
a template. A fluorescent tag is cleaved off with each base addition and is detected
to create the sequence.;
NCI Metathesaurus CUI : CL544866;
Origin ID : C146819;
UMLS CUI : C4687478;
Semantic type(s)
- concept_is_in_subset
