Preferred Label : Illumina Sequencing;
NCIt synonyms : Illumina Sequencing Technology;
NCIt related terms : Illumina;
NCIt definition : A proprietary next-generation DNA sequencing system from Solexa that uses reversible
terminator nucleotides. The genomic DNA to be sequenced is fragmented and ligated
to adapter molecules on both ends to construct an Illumina-specific adapter library.
PCR amplification of the DNA fragments is then performed using the adapter sequence
as primer. Sequencing is carried out by repeated cycles of adding reversible fluorescent-labelled
nucleotide and incorporation of the nucleotides to the complementary strand. The fluorescence
of the incorporated nucleotides is detected.;
NCI Metathesaurus CUI : CL544864;
Origin ID : C146817;
UMLS CUI : C4687476;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- concept_is_in_subset
