Activating ROS1 Gene Mutation

Preferred Label : Activating ROS1 Gene Mutation;

NCIt synonyms : Activating c-ros-1 Gene Mutation; Activating ROS Gene Mutation; Activating MCF3 Gene Mutation; Activating ROS Proto-Oncogene 1, Receptor Tyrosine Kinase Gene Mutation;

NCIt definition : A change in the nucleotide sequence of the ROS1 gene that that results in constitutive activation of both proto-oncogene tyrosine-protein kinase ROS and its downstream signaling pathways.;

NCI Metathesaurus CUI : CL544701;

Details

Origin ID

C146723;

UMLS CUI

C4687441;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
molecular_abnormality_involves_gene
- ROS1 Gene [NCIt concept]
- Receptor Tyrosine Kinase Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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