Preferred Label : A/J Mouse;
NCIt synonyms : A J;
NCIt related terms : A/J;
NCIt definition : Derived by Strong (1921) from a cross between the Cold Spring harbor and Bagg Albino
stocks. The A strain mouse has an albino coat (genotype a,b,c) and is susceptible
to carcinogen-induced lung adenomas and cleft palate formation in response to cortisone.
Also, the strain has defective macrophage function reminiscent of lps mutation common
to other strains. The A strain has intermediate breeding performance with a high ratio
of females at birth and a low litter size at weaning.;
Alternative definition : CDISC: Derived by Strong (1921) from a cross between the Cold Spring harbor and Bagg
Albino stocks. The A strain mouse has an albino coat (genotype a,b,c) and is susceptible
to carcinogen-induced lung adenomas and cleft palate formation in response to cortisone.
Also, the strain has defective macrophage function reminiscent of lps mutation common
to other strains.;
Origin ID : C14650;
UMLS CUI : C1510707;
Automatic exact mappings (from CISMeF team)
Semantic type(s)
concept_is_in_subset