Preferred Label : Dexniguldipine;
NCIt synonyms : ((-)-3-Methyl-5- 3-(4,4-diphenyl-l-piperidinyl)-propyl-l,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylate-hydrochloride); (S)-( )-Watanidipine Hydrochloride; (R)-Nigaldipine Hydrochloride; DNIG; Dexniguldipine Hydrochloride; 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid, 3-(4,4-Diphenyl-1-piperidinyl)propyl
Methyl Ester, Monohydrochloride (R)-;
NCIt related terms : Dexniguldipine.HCl;
NCIt definition : Dexniguldipine is the ( )-enantiomer of the dihydropyridine derivate niguldipine.
Dexniguldipine showed a binding affinity to the P-glycoprotein and therefore it is
to be assumed to block the P-glycoprotein pumping mechanism and to modulate multidrug
resistance. (NCI);
UNII : N9DG6ZTC43;
InChIKey : SVJMLYUFVDMUHP-MGBGTMOVSA-N;
CAS number : 120054-86-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 120054-86-6
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G-SRS /a ;
Molecule name : B8509-035; B859 35; B 859-35;
Chemical formula : C36H39N3O6;
Codes from synonyms : 20026;
Origin ID : C1465;
UMLS CUI : C0208704;
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- is_component_of_chemotherapy_regimen