Dexniguldipine

Preferred Label : Dexniguldipine;

NCIt synonyms : B8509-035 Base Form; B 859-35 Base Form; B859 35 Base Form; DNIG; ( )-(R)-3-(4,4-Diphenylpiperidino)Propyl Methyl 1,4-Dihydro-2,6-Dimethyl-4-(M-Nitrophenyl)-3,5-Pyridinedicarboxylate;

NCIt definition : Dexniguldipine is the ( )-enantiomer of the dihydropyridine derivate niguldipine. Dexniguldipine showed a binding affinity to the P-glycoprotein and therefore it is to be assumed to block the P-glycoprotein pumping mechanism and to modulate multidrug resistance. (NCI);

UNII : N9DG6ZTC43;

InChIKey : SVJMLYUFVDMUHP-MGBGTMOVSA-N;

CAS number : 120054-86-6;

Chemical formula : C36H39N3O6;

Details

Origin ID

C1465;

UMLS CUI

C0208704;

Automatic exact mappings (from CISMeF team)
- niguldipine [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- dexniguldipine [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- dexniguldipine [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Dexniguldipine Hydrochloride [NCIt concept]
is_component_of_chemotherapy_regimen
- Dexamethasone/Dexniguldipine/Doxorubicin/Prednisone/Vincristine [NCIt concept]
- Dexamethasone/Dexniguldipine/Doxorubicin/Vincristine [NCIt concept]
is_free_acid_or_base_form_of
- Dexniguldipine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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