Preferred Label : DBA/1 Mouse;
NCIt synonyms : DBA 1;
NCIt related terms : DBA/1;
NCIt definition : Derived from crosses made by Little in 1929-1930 between DBA progenitors. The DBA/1
mouse has a q H2 haplotype and carries the Cdh23 ahl mutation that results in progressive
hearing loss after 10 months of age. The DBA/1 and DBA/2 mice differ at loci Car2,
Ce2, Hc, H2, If1, Lsh, Tla, and Qa3. The strain is commonly used as a model for rheumatoid
arthritis as it mimics hallmarks of the human disease when immunized with type II
collagen.;
Alternative definition : CDISC: Derived from crosses made by Little in 1929-1930 between DBA progenitors. The
DBA/1 mouse has a q H2 haplotype and carries the Cdh23 ahl mutation that results in
progressive hearing loss after 10 months of age. The DBA/1 and DBA/2 mice differ at
loci Car2, Ce2, Hc, H2, If1, Lsh, Tla, and Qa3. The strain is commonly used as a model
for rheumatoid arthritis as it mimics hallmarks of the human disease when immunized
with type II collagen. (NCI);
Origin ID : C14606;
UMLS CUI : C1511646;
Semantic type(s)
concept_is_in_subset