Preferred Label : DBA/2 Mouse;
NCIt synonyms : DBA 2;
NCIt related terms : DBA/2;
NCIt definition : Derived from crosses made by Little in 1929-1930 between DBA progenitors. The DBA/2
mouse has a d H2 haplotype and carries the Cdh23ahl mutation that results in a progressive
hearing loss beginning at 3-4 weeks of age and severe hearing loss after 3 months
of age. Alleles GpnmbR150X and Tyrp1isa contribute to an eye phenotype that closely
resembles human hereditary glaucoma. The DBA/2 mouse strain shows severe intolerance
to alcohol and morphine and is naturally CD94 deficient.;
Alternative definition : CDISC: Derived from crosses made by Little in 1929-1930 between DBA progenitors. The
DBA/2 mouse has a d H2 haplotype and carries the Cdh23ahl mutation that results in
a progressive hearing loss beginning at 3-4 weeks of age and severe hearing loss after
3 months of age. Alleles GpnmbR150X and Tyrp1isa contribute to an eye phenotype that
closely resembles human hereditary glaucoma. The DBA/2 mouse strain shows severe intolerance
to alcohol and morphine and is naturally CD94 deficient. (NCI);
Origin ID : C14604;
UMLS CUI : C1511649;
Semantic type(s)
- concept_is_in_subset
