NCIt definition : A cloning vector based upon elements of yeast chromosomes. At a minimum these include:
yeast telomeres, a yeast centromere, and a yeast autonomously replicating sequence
(ARS). Such vectors are propagated in yeast and then transferred into a target eukaryotic
cell where the yeast sequences can be recognized and will maintain the molecule through
cell division. These vectors can maintain extremely large amounts of foreign DNA.
YACs are maintained as linear molecules;