Preferred Label : FVB/N Mouse;
NCIt synonyms : FVB N;
NCIt related terms : FVB/N;
NCIt definition : NIH general purpose Swiss mice were selected for resistance or sensitivity to histamine
challenge following pertussis vaccination. The sensitive strain, HFSF/N, was subsequently
found to have the Fv1b allele, which sensitizes the mice to B strain Friend Leukemia
virus. The FVB/N strain has an albino coat with genotype A,B,c,D,P, and has a vigorous
reproductive performance. This strain is commonly used in the generation of transgenic
mice due to the fact that the pronuclei of FVB/N fertilized oocytes are prominent,
which allows for ease of microinjection.;
Alternative definition : CDISC: NIH general purpose Swiss mice were selected for resistance or sensitivity
to histamine challenge following pertussis vaccination. The sensitive strain, HFSF/N,
was subsequently found to have the Fv1b allele, which sensitizes the mice to B strain
Friend Leukemia virus. The FVB/N strain has an albino coat with genotype A,B,c,D,P,
and has a vigorous reproductive performance.;
Origin ID : C14474;
UMLS CUI : C1517102;
Semantic type(s)
- concept_is_in_subset
