" /> Carzelesin - CISMeF





Preferred Label : Carzelesin;

NCIt synonyms : 2-Benzofurancarboxamide, N-(2-((1-(chloromethyl)-1,6-dihydro-8-methyl-5-(((phenylamino)carbonyl)oxy)benzo(1,2-b:4,3-b')dipyrrol-3(2H)-yl)carbonyl)-1H-indol-5-yl)-6-(diethylamino)-, (S)-;

NCIt definition : A cyclopropylpyrroloindole prodrug analogue and DNA minor groove binding agent, with antineoplastic activity. After hydrolysis, the cyclopropyl group of carzelesin alkylates N3-adenine in a sequence-selective fashion. This results in tumor growth inhibition.;

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called alkylating agents.;

UNII : 668UF07O1P;

InChIKey : BBZDXMBRAFTCAA-AREMUKBSSA-N;

CAS number : 119813-10-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 119813-10-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : U-80244;

Chemical formula : C41H37ClN6O5;

NSC code : 619029;

Codes from synonyms : NSC0619029; CDR0000045515;

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09/05/2024


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