Endogenous Retrovirus

Preferred Label : Endogenous Retrovirus;

NCIt synonyms : ERV;

NCIt definition : Genetic elements propagated primarily through the germline, with a proviral structure, i.e. the chromosomally-integrated form of retroviruses and regulated by cellular processes. Could be involved in development and serve as progenitors to pathogenic retroviruses. Classified as ecotropic or xenotropic. Ecotropic viruses can be transmitted to cells of the same species and can produce malignancies. Xenotropic viruses cannot infect cells from their host species but are infectious in heterologous species. Cycles of transcription and reverse transcription make the elements mobile and mutagenic.;

Alternative definition : CDISC: Integrated retroviral elements that are transmitted through the germline. (HGNC);

Details

Origin ID

C14334;

UMLS CUI

C0600466;

Automatic exact mappings (from CISMeF team)
- Expiratory reserve volume (observable entity) [SNOMED CT concept]
Currated CISMeF NLP mapping
- endogenous retroviruses [MeSH Descriptor]
- endogenous retroviruses [MeSH concept]
Semantic type(s)
- Virus [UMLS semantic type]
UMLS correspondences (same concept)
- endogenous retroviruses [MeSH concept]
- endogenous retroviruses [MeSH Descriptor]
concept_is_in_subset
- CDISC SDTM Genomic Symbol Type Response Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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