Preferred Label : Allogeneic Nicotinamide-expanded Natural Killer Cells;
NCIt synonyms : Donor Nicotinamide expanded-Natural Killer Cells; Allogeneic NAM NKs; Allogeneic NAM NK Cells;
NCIt definition : Allogeneic, nicotinamide (NAM)-expanded natural killer (NK) cells, with potential
cytolytic and antineoplastic activities. Upon administration, the allogeneic NAM-expanded
NK cells may lyse cancer cells. These cells also secrete pro-inflammatory cytokines,
which further stimulate an anti-tumor immune response. Ex-vivo treatment with the
vitamin B3 derivative NAM increases the in-vivo homing, retention and proliferation
potential of the NK cells.;
NCI Metathesaurus CUI : CL541606;
Origin ID : C143157;
UMLS CUI : C4684971;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
