Vapreotide - CISMeF

Preferred Label : Vapreotide;

NCIt definition : A synthetic cyclic octapeptide analogue of somatostatin with direct and indirect antitumor effects. Vapreotide binds to somatostatin receptors (SSTR), specifically SSTR-2 and to SSTR-5 with a lesser affinity, in the similar behaviors as other octapeptide somatostatin analogues. Like octreotide, this agent has direct and indirect antitumor effects via inhibiting the release of growth hormone and other peptides that regulate release of insulin, gastrointestinal hormones. Furthermore, vapreotide may also be useful for inducing hemostasis in cases of acute hemorrhage of the upper gastrointestinal tract.;

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called somatostatin analogs.;

UNII : 2PK59M9GFF;

CAS number : 103222-11-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 103222-11-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Docrised;

Molecule name : BMY-41606; RC-160;

Chemical formula : C57H70N12O9S2;

Codes from synonyms : CDR0000045008;

PubMed : 16917205;

Details

Origin ID

C1429;

UMLS CUI

C0164678;

Automatic exact mappings (from CISMeF team)
- Vapreotide [ICD-11 Extension code]
- Wrist [LOINC System]
- Wrist [LOINC System]
- wrist [MeSH Descriptor]
Currated CISMeF NLP mapping
- vapreotide [MeSH concept]
- vapreotide [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- vapreotide [ATC Code]
- vapreotide [MeSH Supplementary Concept]
- vapreotide [MeSH concept]
Validated automatic mappings to BTNT
- vapreotide [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Vapreotide Acetate [NCIt concept]
is_free_acid_or_base_form_of
- Vapreotide Acetate [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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