Preferred Label : Group Sequential Design;
NCIt related terms : SEQUENTIAL;
NCIt definition : A type of clinical investigation format that evaluates data at predefined stages or
after a specific number of patients have participated with specific stopping criteria
based on statistical significance.;
Alternative definition : CDISC: A type of adaptive trial design that allows successive interim analyses of
the data at particular time points or after a pre-defined number of patients have
been enrolled. (CDISC Glossary); CDISC-GLOSS: A type of adaptive trial design that allows successive, unscheduled interim
analyses of the data at particular time points or after a pre-defined number of patients
have been enrolled. NOTE: This kind of trial design is chosen to allow for spontaneous
interim analyses, in order to, for example, determine whether to stop the trial, adjust
the sample size, adjust the dose, or otherwise amend the protocol. [After https://toolbox.eupati.eu/glossary/group-sequential-design/;
https://www.statisticshowto.com/group-sequential-design/; https://toolkit.ncats.nih.gov/glossary/group-sequential-trial/]
See also interim analysis(es), adaptive design, Bayesian statistics, Bayesian approaches.;
NCI Metathesaurus CUI : CL540470;
Origin ID : C142568;
UMLS CUI : C4553402;
Semantic type(s)
- concept_is_in_subset
