Adverse Drug Reaction

Preferred Label : Adverse Drug Reaction;

NCIt synonyms : ADR;

NCIt related terms : adverse drug experience; adverse drug reaction (ADR);

NCIt definition : Any detrimental or unintended response associated with the use of a medication in humans.;

Alternative definition : CDISC-GLOSS: Any noxious and unintended response associated with the use of a drug in humans. NOTE: 1. Post-approval: an adverse event that occurs at doses normally used in man for prophylaxis, diagnosis, or therapy of diseases or for modification of physiological function. 2. Pre-approval: an adverse event that occurs at any dose and where a causal relationship is at least a reasonable possibility. 3. FDA 21 CFR 310.305 defines an adverse drug experience to include any adverse event, whether or not considered to be drug-related. CDISC recognizes that current usage incorporates the concept of causality. [WHO Technical Report 498(1972); ICH E2A];

Details

Origin ID

C142385;

UMLS CUI

C0041755;

Automatic exact mappings (from CISMeF team)
- ADR (body structure) [SNOMED CT concept]
- ferredoxin reductase [ORDO Gene]
Currated CISMeF NLP mapping
- Adverse drug reaction [MedDRA Preferred Term]
- Adverse drug reaction [LOINC component]
- Adverse drug reaction NOS [MedDRA LLT]
- Adverse drug reactions [OMIConto structure]
- Adverse drug response [HPO term]
- Adverse reaction caused by drug (disorder) [SNOMED CT concept]
- Drug side effect [MedDRA LLT]
- Drug-Related side effects and adverse reactions [MeSH Descriptor]
- Harmful effects of drugs, medicaments or biological substances, not elsewhere classified [ICD-11 Category]
- adverse drug reaction [ICPS Descriptor]
- adverse effect medical agent [ICPC-2 Rubric]
- drug adverse effects [CISMeF Querying Strategy]
- drug reaction, nos [SNOMED Notion]
See also inter- (CISMeF)
- Drug toxicity [MedDRA LLT]
- No adverse drug reaction [MedDRA LLT]
- adverse effects [MeSH Qualifier]
- drug toxicity [Disease (Nov.)]
- drug toxicity [MeSH concept]
Semantic type(s)
- Pathologic Function [UMLS semantic type]
UMLS correspondences (same concept)
- Adverse drug reaction [MedDRA Preferred Term]
- Adverse drug reaction [LOINC component]
- Adverse drug reaction NOS [MedDRA LLT]
- Adverse drug response [HPO term]
- Adverse reaction caused by drug (disorder) [SNOMED CT concept]
- Drug reaction (qualifier value) [SNOMED CT concept]
- Drug side effect [MedDRA LLT]
- Drug-Related side effects and adverse reactions [MeSH Descriptor]
- drug reaction, nos [SNOMED Notion]
- drug reactions [MedlinePlus Topic]
Validated automatic mappings to NTBT
- Drug reaction (qualifier value) [SNOMED CT concept]
- drug reactions [MedlinePlus Topic]
concept_is_in_subset
- CDISC Glossary Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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