Perfosfamide - CISMeF

Preferred Label : Perfosfamide;

NCIt synonyms : Hydroperoxycyclophosphamide; 4'-Hydroperoxycyclophosphamide; cis-2-[bis(2-chloroethyl)amino]tetrahydro-3H-1,3,2-oxazaphosphorin-4-yl hydroperoxide P-oxide; 2-[bis(2-chloroethyl)amino]-4-hydroperoxytetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide; 4-Pergamid; 4-HC; cis-4-hydroperoxycyclophosphamide;

NCIt related terms : 4-Hydroperoxycyclophosphamide;

NCIt definition : The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. Perfosfamide alkylates DNA, thereby inhibiting DNA replication and RNA and protein synthesis. (NCI04);

UNII : U880A4FUDA;

InChIKey : VPAWVRUHMJVRHU-VGDKGRGNSA-N;

CAS number : 39800-16-3;

Drug name : Pergamid;

Chemical formula : C7H15Cl2N2O4P;

NSC code : 181815;

ChEBI ID : CHEBI:196991;

Codes from synonyms : NSC0181815; 30297;

Details

Origin ID

C1423;

UMLS CUI

C0163054;

Currated CISMeF NLP mapping
- perfosfamide [MeSH concept]
- perfosfamide [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- perfosfamide [MeSH concept]
- perfosfamide [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients