SETD1B wt Allele

Preferred Label : SETD1B wt Allele;

NCIt synonyms : Set1B; KIAA1076; SET Domain Containing 1B wt Allele; KMT2G;

NCIt definition : Human SETD1B wild-type allele is located in the vicinity of 12q24.31 and is approximately 29 kb in length. This allele, which encodes histone-lysine N-methyltransferase SETD1B protein, plays a role in methylation of histone H3.;

NCIt note : Mutation of the SETD1B gene may be associated with diffuse large B-cell lymphoma (DLBCL). (Cell. 2017;171:481-494.e15.);

NCI Metathesaurus CUI : CL540226;

GenBank Accession Number : AB028999;

Details

Origin ID

C142222;

UMLS CUI

C4553359;

Automatic exact mappings (from CISMeF team)
- SET domain containing 1B, histone lysine methyltransferase [ORDO Gene]
- Set domain-containing protein 1b [OMIM gene]
OMIM relation
- Set domain-containing protein 1b [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 12q24.31 [NCIt concept]
gene_is_element_in_pathway
- Lysine Degradation Pathway [NCIt concept]
gene_plays_role_in_process
- Chromatin Remodeling [NCIt concept]
- Gene Expression [NCIt concept]
- Histone Methylation [NCIt concept]
- Methylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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