Activating AKT1 Gene Mutation

Preferred Label : Activating AKT1 Gene Mutation;

NCIt synonyms : Activating AKT Gene Mutation; AKT1 Activating Mutation; Activating v-akt Murine Thymoma Viral Oncogene Homolog 1 Gene Mutation;

NCIt definition : A change in the nucleotide sequence of the AKT1 gene that that results in constitutive activation of RAC-alpha serine/threonine-protein kinase and its downstream signaling pathways.;

NCI Metathesaurus CUI : CL540111;

Details

Origin ID

C142115;

UMLS CUI

C4684420;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_mutant_encodes_gene_product_sequence_variation
- AKT1 Protein Variant [NCIt concept]
molecular_abnormality_involves_gene
- AKT1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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