Preferred Label : Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v8;
NCIt definition : Stage IV includes: IVA1 (T1-4, N0-2, M0, B2); IVA2 (T1-4, N3, M0, B0-2); IVB (T1-4,
N0-3, M1, B0-2). T1: Limited patches, papules, and/or plaques covering less than 10%
of the skin surface. T2: Patches, papules, or plaques covering 10% or more of the
skin surface. T3: One or more tumors (equal or greater than 1 cm in diameter). T4:
Confluence of erythema covering 80% or more of body surface area. N0: No clinically
abnormal peripheral lymph nodes; biopsy not required. N1: Clinically abnormal peripheral
lymph nodes; histopathology Dutch grade 1 or National Cancer Institute (NCI) LN0-2.
N2: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI
LN3. N3: Clinically abnormal peripheral lymph nodes; histopathology Dutch grades 3-4
or NCI LN4; clone positive or negative. M0: No visceral organ involvement. M1: Visceral
involvement (must have pathology confirmation and organ involved should be specified).
B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes
are atypical (Sezary cells). B1: Low blood tumor burden: more than 5% of peripheral
blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2.
B2: High blood tumor burden: 1,000 per microliter or more Sezary cells with positive
clone. (AJCC 8th ed.);
Neoplastic status : Malignant;
NCI Metathesaurus CUI : CL539448;
Origin ID : C141356;
UMLS CUI : C4683748;
Disease excludes abnormal cell
- Disease excludes normal cell origin
- Has associated anatomic sites
- Semantic type(s)
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_is_stage
- disease_may_have_molecular_abnormality
