Preferred Label : Stage IVA2;
NCIt related terms : IVA2;
NCIt definition : A mycosis fungoides/Sezary syndrome stage defined as follows: T1-4, N3, M0, B0-2.
T1: Limited patches, papules, and/or plaques covering less than 10% of the skin surface.
T2: Patches, papules, or plaques covering 10% or more of the skin surface. T3: One
or more tumors (equal or greater than 1 cm in diameter). T4: Confluence of erythema
covering 80% or more of body surface area. N3: Clinically abnormal peripheral lymph
nodes; histopathology Dutch grades 3-4 or NCI LN4; clone positive or negative. M0:
No visceral organ involvement. B0: Absence of significant blood involvement: 5% or
less of peripheral blood lymphocytes are atypical (Sezary cells). B1: Low blood tumor
burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but
does not meet the criteria of B2. B2: High blood tumor burden: 1,000 per microliter
or more Sezary cells with positive clone. (AJCC 8th ed.);
Origin ID : C141345;
UMLS CUI : C3869908;
Semantic type(s)
- is_stage_of_disease
