Preferred Label : Phosphorylated Proto-Oncogene Tyrosine-Protein Kinase Src;
NCIt synonyms : Phospho-Src; Phospho-Proto-Oncogene Tyrosine-Protein Kinase Src; Phosphorylated SRC;
NCIt definition : A post-translationally modified form of proto-oncogene tyrosine-protein kinase Src
where one or more serine, threonine and/or the tyrosine residues are phosphorylated.
Phosphorylation of the tyrosine at residue position 530 inhibits Src kinase activity,
while phosphorylation of the tyrosine at residue position 419 results in Src activation.;
NCI Metathesaurus CUI : CL539311;
Origin ID : C141264;
UMLS CUI : C4683669;
Semantic type(s)
- concept_is_in_subset
- related_to_genetic_biomarker
