Stage IVB Thyroid Gland Anaplastic Carcinoma AJCC v8

Preferred Label : Stage IVB Thyroid Gland Anaplastic Carcinoma AJCC v8;

NCIt synonyms : Stage IVB Thyroid Gland Undifferentiated (Anaplastic) Carcinoma AJCC v8;

NCIt related terms : Undifferentiated (Anaplastic) Stage IVB Thyroid Gland Cancer;

NCIt definition : Stage IVB includes: (T1-T3a, N1, M0); (T3b, Any N, M0); (T4, Any N, M0). T1: Tumor measuring 2 cm or less in greatest dimension limited to the thyroid. T2: Tumor measuring more than 2 cm but 4 cm or less in greatest dimension limited to the thyroid. T3a: Tumor measuring more than 4 cm in greatest dimension limited to the thyroid. T3b: Gross extrathyroidal extension invading only strap muscles (sternohyoid, sternothyroid, thyrohyoid, or omohyoid muscles) from a tumor of any size. T4: Tumor of any size with gross extrathyroidal extension. N1: Metastasis to regional nodes. M0: No distant metastasis. (from AJCC 8th Ed.);

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL539048;

Details

Origin ID

C141003;

UMLS CUI

C4553881;

Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- Coagulative Necrosis [NCIt concept]
- Dysphagia [NCIt concept]
- Dyspnea [NCIt concept]
- Hoarseness [NCIt concept]
- Vocal Cord Paralysis [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Glandular Differentiation [NCIt concept]
- Squamous Differentiation [NCIt concept]
disease_has_abnormal_cell
- Anaplastic Carcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Epithelial Large Cell [NCIt concept]
- Malignant Epithelial Spindle Cell [NCIt concept]
- Malignant Epithelioid Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Undifferentiated Carcinoma Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Rapidly Enlarging Mass [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Thyroid Gland Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
disease_is_stage
- AJCC v8 Stage [NCIt concept]
- Stage IVB [NCIt concept]
disease_may_have_molecular_abnormality
- BRAF NP_004324.2:p.V600E [NCIt concept]
- HRAS Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- NRAS Gene Mutation [NCIt concept]
- PTEN Gene Inactivation [NCIt concept]
- TERT Promoter Mutation [NCIt concept]
- TP53 Gene Mutation [NCIt concept]

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