Rifabutin - CISMeF

Preferred Label : Rifabutin;

NCIt related terms : Mycobutin;

NCIt definition : A semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription. (NCI04);

Alternative definition : NCI-GLOSS: A drug used to prevent the spread of a bacterium called in patients with advanced HIV (the virus that causes AIDS) infection. It blocks an enzyme that the bacteria need to grow. It is a type of antibiotic.;

UNII : 1W306TDA6S;

InChIKey : ATEBXHFBFRCZMA-VXTBVIBXSA-N;

CAS number : 72559-06-9;

Drug name : Mycobutin;

Molecule name : LM-427;

Chemical formula : C46H62N4O11;

ChEBI ID : CHEBI:45367;

Codes from synonyms : CDR0000663313; CDR0000663309;

Details

Origin ID

C1408;

UMLS CUI

C0140575;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing rifabutin (medicinal product) [SNOMED CT concept]
- Rifabutin [ICD-11 Extension code]
- Rifabutin [LOINC component]
- Rifabutin (substance) [SNOMED CT concept]
- rifabutin [ATC Code]
- rifabutin [MeSH concept]
- rifabutin [MeSH Descriptor]
Validated automatic mappings to BTNT
- rifabutin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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