Preferred Label : Pathologic Stage II Retinoblastoma AJCC v8;
NCIt definition : Stage II includes: pT4, pN0, cM0, Any H. pT4: Evidence of extraocular tumor: tumor
at the transected end of the optic nerve, tumor in the meningeal spaces around the
optic nerve, full-thickness invasion of the sclera with invasion of the episclera,
adjacent adipose tissue, extraocular muscle, bone, conjunctiva, or eyelids. pN0: No
lymph node involvement. cM0: No signs or symptoms of intracranial or distant metastasis.
HX: Unknown or insufficient evidence of a constitutional RB1 gene mutation. H0: Normal
RB1 alleles in blood tested with demonstrated high-sensitivity assays. H1: Bilateral
retinoblastoma, retinoblastoma with an intracranial primitive neuroectodermal tumor
(i.e., trilateral retinoblastoma), patient with family history of retinoblastoma,
or molecular definition of a constitutional RB1 gene mutation. (AJCC 8th ed.);
Neoplastic status : Malignant;
NCI Metathesaurus CUI : CL538907;
Origin ID : C140758;
UMLS CUI : C4683238;
Disease may have findings
- Has associated anatomic sites
- Semantic type(s)
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_molecular_abnormality
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_is_stage
- disease_mapped_to_gene
- disease_may_have_cytogenetic_abnormality
- disease_may_have_molecular_abnormality
