Preferred Label : Pathologic Stage I Retinoblastoma AJCC v8;
NCIt definition : Stage I includes: pT1, pT2, pT3, pN0, cM0, Any H. pT1: Intraocular tumor(s) without
any local invasion, focal choroidal invasion, or pre-or intralaminar involvement of
the optic nerve head. pT2: Intraocular tumor(s) with local invasion. pT3: Intraocular
tumor(s) with significant local invasion. pN0: No lymph node involvement. cM0: No
signs or symptoms of intracranial or distant metastasis. HX: Unknown or insufficient
evidence of a constitutional RB1 gene mutation. H0: Normal RB1 alleles in blood tested
with demonstrated high-sensitivity assays. H1: Bilateral retinoblastoma, retinoblastoma
with an intracranial primitive neuroectodermal tumor (i.e., trilateral retinoblastoma),
patient with family history of retinoblastoma, or molecular definition of a constitutional
RB1 gene mutation. (AJCC 8th ed.);
Neoplastic status : Malignant;
NCI Metathesaurus CUI : CL538908;
Origin ID : C140757;
UMLS CUI : C4683237;
- Disease may have findings
- Has associated anatomic sites
- Semantic type(s)
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_molecular_abnormality
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_is_stage
- disease_mapped_to_gene
- disease_may_have_cytogenetic_abnormality
- disease_may_have_molecular_abnormality