Preferred Label : Clinical Stage III Retinoblastoma AJCC v8;
NCIt definition : Stage III includes: (cT4b, cN0, cM0, Any H); (Any cT, cN1, cM0, Any H). cT4b: Extraocular
tumor clinically evident with proptosis and/or an orbital mass. cN0: No regional lymph
node involvement. cN1: Evidence of preauricular, submandibular, and cervical lymph
node involvement. cM0: No signs or symptoms of intracranial or distant metastasis.
HX: Unknown or insufficient evidence of a constitutional RB1 gene mutation. H0: Normal
RB1 alleles in blood tested with demonstrated high-sensitivity assays. H1: Bilateral
retinoblastoma, retinoblastoma with an intracranial primitive neuroectodermal tumor
(i.e., trilateral retinoblastoma), patient with family history of retinoblastoma,
or molecular definition of a constitutional RB1 gene mutation. (AJCC 8th ed.);
Neoplastic status : Malignant;
NCI Metathesaurus CUI : CL538911;
Origin ID : C140754;
UMLS CUI : C4683234;
Disease may have findings
- Has associated anatomic sites
- Semantic type(s)
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_molecular_abnormality
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_is_stage
- disease_mapped_to_gene
- disease_may_have_cytogenetic_abnormality
- disease_may_have_molecular_abnormality
