Preferred Label : Anatomic Stage III Breast Cancer AJCC v8;
NCIt synonyms : Anatomic Stage III Breast Carcinoma AJCC v8;
NCIt related terms : Stage III Breast Cancer;
NCIt definition : Stage III includes: IIIA: (T0, N2, M0); (T1, N2, M0); (T2, N2, M0); (T3, N1, M0);
(T3, N2, M0); IIIB: (T4, N0, M0); (T4, N1, M0); (T4, N2, M0); IIIC: (Any T, N3, M0).
T0: No evidence of primary tumor. T1: Tumor measuring 20 mm or less in greatest dimension.
T2: Tumor measuring more than 20 mm, but not more than 50 mm in greatest dimension.
T3: Tumor measuring more than 50 mm in greatest dimension. T4: Tumor of any size with
direct extension to the chest wall and/or to the skin (ulceration or macroscopic nodules);
invasion of the dermis alone does not qualify as T4. N0: No regional lymph node metastasis
is identified or isolated tumor cell clusters (ITCs) are identified only. N1: Tumor
with micrometastases; or metastases in 1-3 axillary lymph nodes; and/or clinically
negative internal mammary nodes with micrometastases or macrometastases by sentinel
lymph node biopsy. N2: Tumor with metastases in 4-9 axillary lymph nodes; or positive
ipsilateral internal mammary lymph nodes by imaging in the absence of axillary lymph
node metastases. N3: Tumor with metastases in 10 or more axillary lymph nodes; or
in infraclavicular (level III axillary) lymph nodes; or positive ipsilateral internal
mammary lymph nodes by imaging in the presence of one or more positive level I, II
axillary lymph nodes; or in more than three axillary lymph nodes and micrometastases
or macrometastases by sentinel lymph node biopsy in clinically negative ipsilateral
internal mammary lymph nodes; or in ipsilateral supraclavicular lymph nodes. M0: No
clinical or radiographic evidence of distant metastases. Imaging studies are not required
to assign the M0 category. (AJCC 8th ed.);
Neoplastic status : Malignant;
NCI Metathesaurus CUI : CL526933;
Origin ID : C139541;
UMLS CUI : C4528557;
Automatic exact mappings (from CISMeF team)
- Disease excludes abnormal cell
- Has associated anatomic sites
- Semantic type(s)
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_is_stage
