Mitomycin B - CISMeF

Preferred Label : Mitomycin B;

NCIt synonyms : Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-8-(hydroxymethyl)-6-methoxy-1,5-dimethyl-, 8-carbamate;

NCIt definition : A methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus. Bioreduced mitomycin B generates oxygen radicals, alkylates DNA, and produces interstrand DNA cross-links, thereby inhibiting DNA synthesis. (NCI04);

UNII : VT1IGL3D7V;

InChIKey : UZUUQCBCWDBYCG-DQRAMIIBSA-N;

CAS number : 4055-40-7;

Chemical formula : C16H19N3O6;

NSC code : 75987;

Codes from synonyms : NSC0075987;

Details

Origin ID

C1392;

UMLS CUI

C0128596;

Automatic exact mappings (from CISMeF team)
- mitomycin A [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- mitomycin B [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- mitomycin B [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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