Breast Implant-Associated Anaplastic Large Cell Lymphoma - CISMeF
Breast Implant-Associated Anaplastic Large Cell LymphomaNCIt concept
Preferred Label : Breast Implant-Associated Anaplastic Large Cell Lymphoma;
NCIt synonyms : BIA-ALCL;
NCIt related terms : Breast Implant Associated Anaplastic Large Cell Lymphoma (BIA ALCL);
NCIt definition : A rare anaplastic large cell lymphoma that develops in individuals with breast implants.
It usually presents as an accumulation of seroma fluid between the implant and the
surrounding fibrous capsule. The median interval from the time of the implant to the
development of lymphoma is approximately 10 years.;
Alternative definition : FDA: A non-Hodgkin lymphoma which is associated with breast implants, and consists
of large anaplastic cells. The WHO diagnostic criteria for BIA-ALCL includes positive
expression of CD30 (CD30 ) and negativity for anaplastic lymphoma kinase (ALK-).;