Preferred Label : Glioma Lysate Vaccine GBM6-AD;
NCIt synonyms : GBM6-AD Lysate Protein Vaccine; Glioma Cell Lysate Vaccine GBM6-AD;
NCIt definition : An allogeneic cell lysate-based vaccine derived from the glioma stem cell line GBM6-AD,
which was isolated from the brain tumor of a patient diagnosed with glioblastoma multiforme
(GBM), with potential immunostimulatory and antineoplastic activities. Upon subcutaneous
administration, the glioma lysate vaccine GBM6-AD exposes the immune system to an
undefined amount of glioma-associated antigens (GAAs), and stimulates the immune system
to mount a specific anti-tumoral, cytotoxic T-lymphocyte (CTL)-mediated response against
the GAA-expressing cells, resulting in glioma cell lysis.;
Molecule name : GBM6-AD;
NCI Metathesaurus CUI : CL526538;
Origin ID : C139000;
UMLS CUI : C4528200;
Semantic type(s)
- concept_is_in_subset
- has_target
