In Situ Follicular Neoplasia

Preferred Label : In Situ Follicular Neoplasia;

NCIt synonyms : FLIS; In Situ Follicular Lymphoma; Follicular Lymphoma In Situ; ISFN; In Situ Follicular B-Cell Neoplasm;

NCIt definition : A follicular neoplasia confined to the germinal centers of the lymph nodes, without evidence of disseminated disease. It is characterized by the replacement of a germinal center by neoplastic centrocytes with uniformly intense positivity for BCL2. The surrounding mantle cuff and lymphoid architecture are intact. It has a low rate of progression to follicular lymphoma, but is often associated with prior or synchronous overt lymphoma.;

Neoplastic status : Uncertain Malignant Potential;

NCI Metathesaurus CUI : CL525716;

Details

Origin ID

C138181;

UMLS CUI

C4524188;

Automatic exact mappings (from CISMeF team)
- Flies [EDAM topic]
- Follicular lymphoma in situ [ICD-11 Subcategory]
- In situ follicular lymphoma [MedDRA LLT]
- In situ follicular neoplasia [MedDRA LLT]
- In situ follicular neoplasia [ICD-11 Extension code]
- In situ follicular neoplasia (morphologic abnormality) [SNOMED CT concept]
- diptera [MeSH Descriptor]
Disease excludes abnormal cell
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- In situ follicular lymphoma [MedDRA LLT]
- In situ follicular neoplasia [MedDRA LLT]
- In situ follicular neoplasia (morphologic abnormality) [SNOMED CT concept]
concept_is_in_subset
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
disease_has_abnormal_cell
- Abnormal Hematopoietic and Lymphoid Cell [NCIt concept]
- Abnormal Lymphocyte [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Follicle Center B-Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Borderline Lesion [NCIt concept]
- In Situ Lesion [NCIt concept]
disease_has_molecular_abnormality
- BCL2 Gene mRNA Overexpression [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Germinal Center B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Germinal Center [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]

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