" /> In Situ Follicular Neoplasia - CISMeF





Preferred Label : In Situ Follicular Neoplasia;

NCIt synonyms : FLIS; In Situ Follicular Lymphoma; Follicular Lymphoma In Situ; ISFN; In Situ Follicular B-Cell Neoplasm;

NCIt definition : A follicular neoplasia confined to the germinal centers of the lymph nodes, without evidence of disseminated disease. It is characterized by the replacement of a germinal center by neoplastic centrocytes with uniformly intense positivity for BCL2. The surrounding mantle cuff and lymphoid architecture are intact. It has a low rate of progression to follicular lymphoma, but is often associated with prior or synchronous overt lymphoma.;

Neoplastic status : Uncertain Malignant Potential;

NCI Metathesaurus CUI : CL525716;

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29/07/2025


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