Preferred Label : T-cell Receptor-engineered T-cells;
NCIt synonyms : T-cell Receptor-engineered T Cells; TCR-engineered T-cells; T-cell Receptor-engineered T-lymphocytes; TCR-modified T Cells; TCR T Cells; TCR T-cells;
NCIt definition : T-lymphocytes that have been engineered to express a modified antigen-specific T-cell
receptor (TCR). In cancer therapy, the TCR-engineered T-cell recognizes a tumor-specific
protein fragment complexed with major histocompatibility complex (MHC) molecules on
the surface of the tumor cells and kills the tumor cell.;
NCI Metathesaurus CUI : CL525717;
Origin ID : C138180;
UMLS CUI : C4527420;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
