APOL1 wt Allele

Preferred Label : APOL1 wt Allele;

NCIt synonyms : APOL; FSGS4; Apolipoprotein L1 wt Allele; APO-L; APOL-I;

NCIt definition : Human APOL1 wild-type allele is located in the vicinity of 22q12.3 and is approximately 15 kb in length. This allele, which encodes apolipoprotein L1 protein, plays a role in the metabolism of cholesterol and other lipids. Variation of the gene is associated increased susceptibility to both focal segmental glomerulosclerosis 4 and non-diabetic end-stage renal disease.;

NCI Metathesaurus CUI : CL525670;

GenBank Accession Number : AF019225;

Details

Origin ID

C138152;

UMLS CUI

C4521365;

Automatic exact mappings (from CISMeF team)
- Apolipoprotein L-i [OMIM gene]
- Focal segmental glomerulosclerosis 4, susceptibility to [OMIM Phenotype]
- apolipoprotein L1 [ORDO Gene]
OMIM relation
- Apolipoprotein L-i [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Cholesterol Homeostasis [NCIt concept]
- Ligand Binding [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Lipid Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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