NCIt definition : A contrast agent composed of lipid microspheres containing an inorganic fluorinated
inert gas comprised of six fluoride atoms bound to one sulfur atom (SF6), with potential
contrast enhancing activity for diagnostic imaging during ultrasound procedures. Upon
administration of the sulfur hexafluoride lipid microspheres, the microspheres are
distributed throughout the bloodstream and into organs. The acoustic impedance of
the lipid microspheres is much lower than that of the surrounding tissue and/or fluids.
Therefore during ultrasound imaging, this agent reflects the ultrasound waves at the
microsphere-tissue interface, which enhances the contrast between the areas where
the microspheres are present and the surrounding tissues or fluids.;