Preferred Label : Antibody-drug Conjugate MEDI7247;
NCIt synonyms : ADC MEDI7247;
NCIt related terms : MEDI-7247;
NCIt definition : An antibody-drug conjugate (ADC) composed of a proprietary monoclonal antibody against
an unnamed tumor-associated antigen (TAA) linked to an as of yet undisclosed cytotoxic
agent, with potential antineoplastic activity. Upon intravenous administration, the
monoclonal antibody moiety of MEDI7247 targets and binds to the TAA expressed on tumor
cells. Upon binding and internalization, the cytotoxic agent is released and kills
the TAA-expressing cancer cells, through an as of yet unknown mechanism of action.;
UNII : XZ66R08EI3;
Molecule name : MEDI 7247; MEDI7247;
NCI Metathesaurus CUI : CL524897;
Origin ID : C137821;
UMLS CUI : C4527229;
Semantic type(s)
- concept_is_in_subset
